Soju Bae
2021-11-07T02:54:21+00:00
现在辉瑞疫苗数据造假曝光,就有点微妙了。甚至莫德纳数据是否真实也不好说。
但是就算效果还可以,研发速度也太慢了,国内市场没剩多少了
国内mrna做得其实都不大好,这玩意儿技术门槛还是高,不过mrna技术以后肯定是主流。长期看好,短期就那样吧
[s:ac:哭笑]现在热点在同济那篇文章能发酵到哪,以及口服啥时候上市。
还炒疫苗脑子怕不是有坑。
你都来大时代了,应该有点信息收集能力吧?少看点自嗨内宣,自己出去多看几篇英文原文报道,那个外包公司临时工举报的是什么,内容都有,就别跟着传谣了行吗
沃森这个目前看只能争取加强针份额,国药和科兴后边的势力看起来是一点都不想和别家分肉吃
不过灭活路线的效力确实低,现在大部分人以为自己在打加强针,其实他是在打第一针。各路专家也在说(暗示)测抗体和混打的事,两边在隔空对峙
那这个预期差就有了,毕竟医保是撑不住每个人半年一针二百多块的,沃森的机会也就在这里
[url]https://www.bmj.com/content/375/bmj.n2635[/url]
有能力的看完吧,这篇辉瑞分包公司Ventavia的举报文章
- Participants placed in a hallway after injection and not being monitored by clinical staff
- Lack of timely follow-up of patients who experienced adverse events
- Protocol deviations not being reported
- Vaccines not being stored at proper temperatures
- Mislabelled laboratory specimens, and
- Targeting of Ventavia staff for reporting these types of problems.
Nine of the trial’s 153 sites were inspected. Ventavia’s sites were not listed among the nine, and no inspections of sites where adults were recruited took place in the eight months after the December 2020 emergency authorisation.
In several cases Ventavia lacked enough employees to swab all trial participants who reported covid-like symptoms, to test for infection. Laboratory confirmed symptomatic covid-19 was the trial’s primary endpoint, the employee noted. (An FDA review memorandum released in August this year states that across the full trial swabs were not taken from 477 people with suspected cases of symptomatic covid-19.)
She told The BMJ that, shortly after Ventavia fired Jackson, Pfizer was notified of problems at Ventavia with the vaccine trial and that an audit took place.
Since Jackson reported problems with Ventavia to the FDA in September 2020, Pfizer has hired Ventavia as a research subcontractor on four other vaccine clinical trials (covid-19 vaccine in children and young adults, pregnant women, and a booster dose, as well an RSV vaccine trial; NCT04816643, NCT04754594, NCT04955626, NCT05035212). The advisory committee for the Centers for Disease Control and Prevention is set to discuss the covid-19 paediatric vaccine trial on 2 November.
怎么还有人说药出了就不用打疫苗的,哪怕你把他当流感看那也是蛋白酶抑制剂+逆转录酶抑制剂(核苷类/非核苷类一起上)+侵入抑制剂一起使用才好使,单单一个药随随便便就能给你把耐药性点了